Free
Radicals...The Destructive Force In Our Bodies
Free radicals (FR) are unstable and highly reactive
molecules which cause oxidative damage in our
bodies.
To illustrate the point, it's similar to leaving a lump of
iron in a glass of water, eventually it will rust
up, and that's exactly what oxidative stress does to our bodies.
These molecules are unstable because they are missing an
electron. So, to try and stabilise themselves, they
steal electrons from any molecule that comes
into contact with them. Quite a battle going on
there!
Success...our free-radical molecule is now balanced, all is
ok.......Hmmmm, not quite!
You see, the molecule that has been robbed now mutates into a
new free-radical.... and so the whole process begins again.
Fact...up to a 100,000 free-radical molecules can be
created in our bodies within a few seconds (scary
stuff)!
Oxidants play many normal roles in our body, it's only their
overproduction (or failure of antioxidant defenses)
that result in harmful oxidative stress (i.e
disease).
New research has shown oxidative damage can be the
trigger for a variety of serious and often deadly
diseases including...
- Breast Cancer
- Prostate Cancer
- Parkinsons Disease
- Rheumatoid Arthritis
- Alzheimers Disease
- Heart Disease and Strokes
- Diabetes
The majority of cancers are probably caused by
free-radical damage to key molecules and
delicate genetic materials (DNA).
We are open to free-radicals from our environment
through...
- Pollution
- Radiation
- Unhealthy Foods
- Bacteria
- Viruses
- Cigarette Smoke
- UV Light
The question is do we have any control over free radical
production?
Enter Antioxidants, our knights in
shining armour, known affectionately as free-radical
scavengers. They seek the enemy out, donate the missing
electrons and put the brakes on the damaging
oxidative chain reaction.
There are many different types of free-radicals in the body, so
a wide range of antioxidants are necessary to
protect against them.
The most powerful and dangerous of the free-radical
is called Superoxide. As we know, free-radicals
need only one electron from a stable molecule to stabilise
itself. But a greedy superoxide free radical requires as
many as three electrons to balance itself.
Black seed oil, apparently, acts as a
potent free-radical scavenger of
superoxide.
So now you understand and can clearly see how vital
antioxidants are in controlling free-radicals.
Check a 'rain check' your current diet, does it consist of
food high in antioxidants? If it does
then brilliant, keep it up, but if not then you are lacking
in those crucial, life saving antioxidants. A diet change is
in order..and fast!
Here are the 5 primary free
radicals:
Peroxyl
The Peroxyl radical is the most commonly measured and the
first free adical measured by an ORAC test. However, just
because it was first, does not mean it is more important than
the other primary radicals. Peroxyl ORAC is a representation of
antioxidant capacity; it does not measure complete or
comprehensive antioxidant capacity. The ability to quench
peroxyl is a meaningful part of the total antioxidant picture,
but it is just a part; measurement of comprehensive antioxidant
capacity must include the other primary radicals as well.
Hydroxyl
Hydroxyl is highly reactive and cannot be eliminated by our
body’s own antioxidant defenses. It can damage virtually all
types of macromolecules, such as, carbohydrates, nucleic acids,
lipids, and amino acids. In the skin, hydroxyl radicals are
created by UV exposure. We need to ingest antioxidants that
quench hydroxyl in order to protect against this harmful
radical. Hydroxyl is measured by the HORAC test.
Peroxynitrite
Peroxynitrite is particularly harmful to proteins. It has
been implicated in the development of various health issues
including inflammation. In the skin, peroxynitrite contributes
to the breakdown of vital proteins, such as collagen. It is
measured by the NORAC test.
Superoxide Anion
Superoxide anion is a precursor of all other reactive oxygen
species. Sometimes referred to as “the mother of free
radicals”, it is highly toxic and contributes to lipid (fat)
and DNA damage. Antioxidants that scavenge superoxide anion
also help prevent the formation of radicals such as hydrogen
peroxide and hydroxyl. Superoxide anion has been linked to
hypertension and cardiovascular damage. It is measured by the
SORAC test.
Singlet Oxygen
In the skin, singlet oxygen is generated by UV. Inside our
bodies it is linked to the oxidation of LDL cholesterol and
poor cardiovascular health. Singlet oxygen is highly unstable
and durable. Carotenoids are very effective at scavenging
singlet oxygen. It is measured by the SOAC test.
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